منابع مشابه
Krebs cycle anions in metabolic acidosis
For many years it has been apparent from estimates of the anion gap and the strong ion gap that anions of unknown identity can be generated in sepsis and shock states. Evidence is emerging that at least some of these are intermediates of the citric acid cycle. The exact source of this disturbance remains unclear, because a great many metabolic blocks and bottlenecks can disturb the anaplerotic ...
متن کاملThin layer chromatography of Krebs cycle acids.
A systematic appraisal of a large number of solvent systems was carried out for the separation of lactic, pyruvic and 3-hydroxybutyric acids and all of the KREBS cycle acids, except oxalosuccinic, using silica gel G and cellulose thin layer Chromatographie plates. Four solvent systems which allowed separation of various combinations of acids are described and the limits of this method of separa...
متن کاملSeifert Fibered Homology 3 - Spheres Mike Krebs
To each connected component in the space of semisimple representations from the orbifold fundamental group of the base orbifold of a Seifert fibered homology 3-sphere into the Lie group U(2, 1), we associate a real number called the “orbifold Toledo invariant.” Using the theory of Higgs bundles, we explicitly compute all values this invariant takes on.
متن کاملRetrospective. Edwin G. Krebs (1918-2009).
537 PERSPECTIVES E dwin G. Krebs, a giant of biomedical science in the 20th century, died on 21 December from congestive heart failure in Seattle at the age of 91. His discovery (with Edmond H. Fischer) of protein phosphorylation as a regulatory mechanism touched all aspects of biomedical science and profoundly infl uenced therapeutic approaches now used in clinical care. Ed's life epitomizes c...
متن کاملSodium-coupled transporters for Krebs cycle intermediates.
Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate are transferred across plasma membranes of cells by secondary active transporters that couple the downhill movement of sodium to the concentrative uptake of substrate. Several transporters have been identified in isolated membrane vesicles and cells based on their functional properties, suggesting the existence of at ...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1933
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1881.53.3_275